A State-of-the-Science Conference for Frontline Health Professionals, Sponsored by Collaborating Federal Health Agencies

HIV THE BASICS

HIV THE BASICS

Friday, May 15, 2009 – 8:00 am – 11:30 am

Session Co-Chairs:	Brian Feit, MPA, Department of Health and Human Services
	Kenneth Mayer, MD, Brown University, Infectious Disease Division

Session Objectives:

Utilize appropriate clinical tests for guiding the care of individuals with HIV
Develop treatment strategies for individuals with HIV based on currently available guidelines
Incorporate strategies for remaining up-to-date on future modifications to the guidelines for managing the care of those with HIV
Identify appropriate ARV regimens for newly diagnosed individuals with HIV based on current evidence

Session Outline:

8:10 am – 8:30 am	History of the Epidemic: Epidemiology: Global and Local US – Then and Now Late presentation and reasons for routine HIV testing Speaker: Ronald Valdiserri, MD, US Department of Veterans Affairs

8:30 am – 9:00 am	Natural History of HIV Infection—Pathogenesis HIV Life Cycle Cell Membrane Receptors and Viral Entry Neutralizing Antibodies, CTLs and other host responses Natural History of Untreated HIV Stages of HIV Infection Speaker: Rajesh Gandhi, MD, Massachusetts General Hospital

9:00 am – 9:30 am	Clinical Tests What they are, What they tell you, Why to use them HIV testing Who to test, where to test, how to test? Elisa Western Blot DNA/RNA testing CD4 Counts Viral Loads Guidelines: Evolving Care/Changing guide When to start treatment (borrow from the IAS and DHHS treatment Guidelines. In fact it could be a perk for the course – each person who attends gets a copy of the IAS and DHHS treatment guidelines in a binder.) Building an Antiretroviral Regimen – Initiation of treatment Where to get updates – AIDS Info Summarize Opportunistic Infection Management Principles and Prophylaxis Speaker: Paul Volberding, MD, San Francisco VA Medical Center

9:30 pm – 10:00am	Q&A / Break

10:00 am – 10:30 am	Medications - Types of Antiretrovirals NRTI (Indications, Benefits, Side effects) NNRTI (Indications, Benefits, Side effects) PI (Indications, Benefits, Side effects) Fusion Inhibitors (Indications, Benefits, Side effects) Integrase Inhibitors New Agents on the horizon Resistance Testing—Genotypic & Phenotypic When to switch Speaker: Richard D’Aquila, MD, Vanderbilt University

10:30 am – 11:00 am	Transmission/Prevention Points of high infectivity, such as during the Acute Retroviral syndrome Primary Prevention Prevention with Positives STDs Post Exposure Prophylaxis Prevention of Maternal To Child Transmission Speaker: Mark Thrun, MD, Denver Health Medical Center

11:00 am – 11:30 am	Consumer Perspective: If you build it, will they come? What consumers really want in care Speaker: Dawn Averitt-Bridge, The Well Project